CR2 monoclonal antibody, clone LT21 (FITC)
产品名称： CR2 monoclonal antibody, clone LT21 (FITC)
英文名称： CR2 monoclonal antibody, clone LT21 (FITC)
产品编号： MAB4390
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CR2.
- Immunogen:
- Native purified CR2 from human B-lymphoblastoid cell line IM9.CR2.
- Host:
- Mouse
- Theoretical MW (kDa):
- 145
- Reactivity:
- Bovine, Human, Pig
- Specificity:
- This antibody reacts with CD21 (CR2), a 145 KDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
- Form:
- Liquid
- Conjugation:
- FITC
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Antiphospholipid syndrome patients display reduced titers of soluble CD21 in their sera irrespective of circulating anti-beta2-glycoprotein-I autoantibodies.
Singh A, Blank M, Shoenfeld Y, Illges H.Rheumatol Int. 2008 May;28(7):661-5. Epub 2008 Jan 3.
- 2.
- Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Zabel MD, Heikenwalder M, Prinz M, Arrighi I, Schwarz P, Kranich J, von Teichman A, Haas KM, Zeller N, Tedder TF, Weis JH, Aguzzi A.J Immunol. 2007 Nov 1;179(9):6144-52.
- 3.
- Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs.
Faldyna M, Samankova P, Leva L, Cerny J, Oujezdska J, Rehakova Z, Sinkora J.Vet Immunol Immunopathol. 2007 Sep 15;119(1-2):56-62. Epub 2007 Jun 26.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 1380
- Gene Name:
- CR2
- Gene Alias:
- C3DR,CD21,SLEB9
- Gene Description:
- complement component (3d/Epstein Barr virus) receptor 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Complement component receptor-2 (CR2) is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. See also CR1 (MIM 120620). Yefenof et al. (1976) [PubMed 181330] found complete overlapping of EBV receptors and C3 (MIM 120700) receptors on human B lymphocytes.[supplied by OMIM
- Other Designations:
- OTTHUMP00000034421,OTTHUMP00000034447