KLK3 polyclonal antibody
产品名称： KLK3 polyclonal antibody
英文名称： KLK3 polyclonal antibody
产品编号： PAB4401
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of KLK3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human KLK3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Polymorphic forms of prostate specific antigen and their interaction with androgen receptor trinucleotide repeats in prostate cancer.
Binnie MC, Alexander FE, Heald C, Habib FK.Prostate. 2005 Jun 1;63(4):309-15.
- 2.
- Serenoa repens (Permixon) inhibits the 5alpha-reductase activity of human prostate cancer cell lines without interfering with PSA expression.
Habib FK, Ross M, Ho CK, Lyons V, Chapman K.Int J Cancer. 2005 Mar 20;114(2):190-4.
- 3.
- Expression of prostate specific membrane antigen in androgen-independent prostate cancer cell line PC-3.
Laidler P, Dulinska J, Lekka M, Lekki J.Arch Biochem Biophys. 2005 Mar 1;435(1):1-14.
- Entrez GeneID:
- 354
- Protein Accession#:
- NP_001639;P07288
- Gene Name:
- KLK3
- Gene Alias:
- APS,KLK2A1,PSA,hK3
- Gene Description:
- kallikrein-related peptidase 3
- Omim ID:
- 176820
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- P-30 antigen,gamma-seminoprotein,kallikrein 3, (prostate specific antigen),prostate specific antigen,semenogelase,seminin
- Interactome
- Gene Pathway
- Related Disease
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Lymphatic Metastasis
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Neoplasm Recurrence, Local
- Neoplasms, Hormone-Dependent
- Prostate cancer
- Prostatic Hyperplasia
- Prostatic Neoplasms