PADI4 polyclonal antibody
产品名称： PADI4 polyclonal antibody
英文名称： PADI4 polyclonal antibody
产品编号： PAB2519
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PADI4.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PADI4.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Comparison of enzymatic properties between hPADI2 and hPADI4.
Nakayama-Hamada M, Suzuki A, Kubota K, Takazawa T, Ohsaka M, Kawaida R, Ono M, Kasuya A, Furukawa H, Yamada R, Yamamoto K.Biochem Biophys Res Commun. 2005 Feb 4;327(1):192-200.
- 2.
- Human PAD4 regulates histone arginine methylation levels via demethylimination.
Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA.Science. 2004 Oct 8;306(5694):279-83. Epub 2004 Sep 2.
- 3.
- A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population.
Barton A, Bowes J, Eyre S, Spreckley K, Hinks A, John S, Worthington J.Arthritis Rheum. 2004 Apr;50(4):1117-21.
- Entrez GeneID:
- 23569
- Protein Accession#:
- NP_036519;Q9UM07
- Gene Name:
- PADI4
- Gene Alias:
- PAD,PAD4,PADI5,PDI4,PDI5
- Gene Description:
- peptidyl arginine deiminase, type IV
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq
- Other Designations:
- HL-60 PAD,OTTHUMP00000002482,PADI-H protein,peptidyl arginine deiminase, type V,protein-arginine deiminase
- Related Disease
- Arthritis
- Arthritis, Rheumatoid
- Asthma
- Autoimmune Diseases
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Chronic Disease
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Immune System Diseases
- Malignant melanoma
- Melanoma
- Multiple Sclerosis