AURKB (Center) Peptide
产品名称： AURKB (Center) Peptide
英文名称： AURKB (Center) Peptide
产品编号： P2414
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of AURKB.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human AURKB.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cell cycle-dependent regulation of the human aurora B promoter.
Kimura M, Uchida C, Takano Y, Kitagawa M, Okano Y.Biochem Biophys Res Commun. 2004 Apr 9;316(3):930-6.
- 2.
- Correcting improper chromosome-spindle attachments during cell division.
Lampson MA, Renduchitala K, Khodjakov A, Kapoor TM.Nat Cell Biol. 2004 Mar;6(3):232-7. Epub 2004 Feb 8.
- 3.
- Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis.
Yasui Y, Urano T, Kawajiri A, Nagata K, Tatsuka M, Saya H, Furukawa K, Takahashi T, Izawa I, Inagaki M.J Biol Chem. 2004 Mar 26;279(13):12997-3003. Epub 2004 Jan 13.
- Applications
- Western Blot (Tissue lysate)
- The AURKB polyclonal antibody (Cat # PAB2807) is used in Western blot to detect AURKB in mouse spleen tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with AURKB polyclonal antibody (Cat # PAB2807) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 9212
- Protein Accession#:
- NP_004208;Q96GD4
- Gene Name:
- AURKB
- Gene Alias:
- AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,STK12,STK5
- Gene Description:
- aurora kinase B
- Omim ID:
- 604970
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM
- Other Designations:
- aurora-1,aurora-B,serine/threonine kinase 12
- Related Disease