CSNK2A1抗体
Applications
In-house applications |
ELISA, WB, IHC, IF, IP Application not tested? Please see our Guarantee. |
Species specificity |
Human,Mouse,Rat; other species not tested. |
Images
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- HeLa cells were subjected to SDS PAGE followed by western blot with 10992-1-AP(CSNK2A1 antibody) at dilution of 1:1000
- Immunohistochemical of paraffin-embedded human gliomas using 10992-1-AP(CSNK2A1 antibody) at dilution of 1:100 (under 10x lens)
- Immunohistochemical of paraffin-embedded human gliomas using 10992-1-AP(CSNK2A1 antibody) at dilution of 1:100 (under 40x lens)
- IP Result of anti-CSNK2A1 (IP:10992-1-AP, 4ug; Detection:10992-1-AP 1:1000) with HeLa cells lysate 2800ug.
- Immunofluorescent analysis of HeLa cells using 10992-1-AP( CSNK2A1 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Positive WB detected in |
HeLa cells, HEK-293 cells, Jurkat cells, NIH/3T3 cells |
Positive IP detected in |
HeLa cells |
Positive IHC detected in |
Human gliomas tissue, human colon cancer tissue |
Positive IF detected in |
HeLa cells |
Recommended dilution |
WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100 |
CSNK2A1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source |
Rabbit |
Purification method |
Antigen affinity purification |
Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information CSNK2A1抗体
Immunogen |
CSNK2A1 fusion protein ag1452 |
Full name |
Casein kinase 2, alpha 1 polypeptide |
Calculated molecular
weight |
45 kDa |
Observed molecular
weight |
45 kDa |
GenBank accession
number |
BC011668 |
Gene ID (NCBI) |
1457 |
Gene symbol |
CSNK2A1 |
Synonyms |
Casein kinase II subunit alpha, CK II alpha, CK2A1, CKII, CSNK2A1 |
Background
CSNK2A1(Casein kinase II subunit alpha) is also named as CK2A1 and belongs to the CK2 subfamily. The CSNK2A1 gene contains 8 exons whose sequences comprise bases 102 to 824 of the coding region of the human casein kinase II alpha subunit. Casein kinase II is a ubiquitous protein-serine/threonine kinase in eukaryotic cells that catalyzes the phosphorylation of many protein substrates and has been regarded as a second-messenger-independent protein kinase. this enzyme is composed of an α subunit (37 to 44kDa) and aβsubunit (24 to 28 kDa) and exists as an α2β2 tetramer.(PMID:1448100). Casein kinase 2 has been found to be inccreased at protein level and up-regulated at the level of enzyme activity in the majority of cancers. However, elevated levels of casein kinase 2 are present in certain normal organs such as brain and testes. CSNK2A1抗体
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