CDKN2D monoclonal antibody, clone DCS-100
产品名称： CDKN2D monoclonal antibody, clone DCS-100
英文名称： CDKN2D monoclonal antibody, clone DCS-100
产品编号： MAB2027
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant CDKN2D.
- Immunogen:
- Recombinant protein corresponding to full length human CDKN2D.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6.
Hirai H, Roussel MF, Kato JY, Ashmun RA, Sherr CJ.Mol Cell Biol. 1995 May;15(5):2672-81.
- Application Image
- Western Blot
- Immunohistochemistry
- Immunoprecipitation
- Entrez GeneID:
- 1032
- Gene Name:
- CDKN2D
- Gene Alias:
- INK4D,p19,p19-INK4D
- Gene Description:
- cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- Omim ID:
- 600927
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq
- Other Designations:
- CDK inhibitor p19INK4d,cell cycle inhibitor, Nur77 associating protein,cyclin-dependent kinase 4 inhibitor D p19,cyclin-dependent kinase inhibitor 2D,inhibitor of cyclin-dependent kinase 4d
- Gene Pathway