FITC标记的EDC3蛋白抗体
产品名称： FITC标记的EDC3蛋白抗体
英文名称： Anti-EDC3/FITC
产品编号： HZ-14491R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-EDC3/FITC Conjugated antibody
FITC标记的EDC3蛋白抗体
| 英文名称 | Anti-EDC3/FITC |
| 中文名称 | FITC标记的EDC3蛋白抗体 |
| 别 名 | EDC 3; edc3; EDC3_HUMAN; enhancer of mRNA decapping 3 homolog (S. cerevisiae); Enhancer of mRNA decapping 3 homolog; Enhancer of mRNA decapping 3, S. cerevisiae, homolog of; Enhancer of mRNA decapping protein 3; Enhancer of mRNA-decapping protein 3; FLJ21128; FLJ31777; hYjeF_N2; hYjeF_N2-15q23; LSM 16; LSM16; LSM16 homolog (EDC3 S. cerevisiae); LSM16 homolog (EDC3, S. cerevisiae); LSM16 homolog; YJDC; YjeF domain containing; YjeF domain containing protein 1; YjeF domain containing protein; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2; YJEFN2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EDC3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008] Edc3, enhancer of mRNA-decapping protein 3, is a 508 amino acid protein that maps to human gene EDC3. Edc3 is a member of the EDC3 family and contains one YjeF N-terminal domain. Edc3 is localized to the cytoplasm and is found primarily in the processing bodies (PBs) of the cell. Evidence indicates Edc3 also interacts with TTP (zinc finger protein 36), a candidate gene for obesity-related metabolic complications. Function: Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis. Subcellular Location: Cytoplasm; P-body. Processing bodies. Tissue Specificity: Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. Similarity: Belongs to the EDC3 family. Contains 1 DFDF domain. Contains 1 YjeF N-terminal domain. Database links: Entrez Gene: 80153 Human Entrez Gene: 453743 Chimpanzee Entrez Gene: 101128321 Gorilla Entrez Gene: 353190 Mouse Entrez Gene: 100171859 Orangutan Omim: 609842 Human SwissProt: Q96F86 Human SwissProt: Q8K2D3 Mouse SwissProt: Q5RDU9 Orangutan Unigene: 682454 Human Unigene: 96852 Human Unigene: 268104 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
EDC3与从5质末端降解前从mRNA中去除5质帽所需的mRNA脱落复合物有关（Fenger-Gron等人，2005[PubMed 16364915]）。
Edc3，mRNA缺失蛋白3的增强子，是一个508个氨基酸的蛋白质，映射到人类基因EDC3。EDC3是EDC3家族的成员，包含一个YJEF N端结构域。EDC3定位于细胞质中，主要存在于细胞的处理体（PBS）中。有证据表明，Edc3还与TTP（锌指蛋白36）相互作用，TTP是肥胖相关代谢并发症的候选基因。