FITC标记的减数分裂核分裂蛋白1/GAJ抗体
产品名称: FITC标记的减数分裂核分裂蛋白1/GAJ抗体
英文名称: Anti-MND1/FITC
产品编号: HZ-7799R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-MND1/FITC Conjugated antibody
FITC标记的减数分裂核分裂蛋白1/GAJ抗体
英文名称 | Anti-MND1/FITC |
中文名称 | FITC标记的减数分裂核分裂蛋白1/GAJ抗体 |
别 名 | GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1309007; 2610034E18Rik; AI591601. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 细胞周期蛋白 细胞分化 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 24kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GAJ/MND1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination. Function: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Subunit: Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA. Subcellular Location: Nucleus (Probable) Similarity: Belongs to the MND1 family. Database links: UniProtKB/Swiss-Prot: Q9BWT6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GAJ基因的产物与HOP2结合形成稳定的异源二聚体复合物,结合DNA并刺激RAD51和DMC1的重组酶活性。MND1和HOP2基因都是减数分裂重组不可缺少的基因。