FITC标记的细胞色素b5抗体
产品名称： FITC标记的细胞色素b5抗体
英文名称： Anti-Cytochrome b5/FITC
产品编号： HZ-5115R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Cytochrome b5/FITC Conjugated antibody
FITC标记的细胞色素b5抗体
| 英文名称 | Anti-Cytochrome b5/FITC |
| 中文名称 | FITC标记的细胞色素b5抗体 |
| 别 名 | CYB 5; CYB 5A; CYB5; CYB5_HUMAN; CYB5A; Cytochrome b 5; Cytochrome b5 (microsomal); Cytochrome b5; Cytochrome b5 type A (microsomal); Cytochrome b5 type A; MCB 5; MCB5; Microsomal cytochrome b5; Microsomal cytochrome b5 type A; Type 1 cyt b5; CYB5A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 细胞定位 | 细胞膜 线粒体 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cytochrome b5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Function: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. Subcellular Location: Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side. Isoform 2: Cytoplasm. DISEASE: Methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]: A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the cytochrome b5 family. Contains 1 cytochrome b5 heme-binding domain. Database links: Entrez Gene: 1528 Human Entrez Gene: 109672 Mouse Entrez Gene: 64001 Rat Omim: 250790 Human Omim: 613218 Human SwissProt: P00167 Human SwissProt: P56395 Mouse SwissProt: Q544Z9 Mouse SwissProt: P00173 Rat Unigene: 465413 Human Unigene: 31018 Mouse Unigene: 1055 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是膜结合的细胞色素，其将铁血红蛋白（铁血红蛋白）还原为亚铁血红蛋白，这是硬脂酰辅酶A脱氢酶活性所必需的。该基因的缺陷是IV型遗传性高铁血红蛋白血症的一个原因。已经发现了三个编码不同亚型的转录本变体。[ RefSeq 2010军提供]