TNFSF10 polyclonal antibody
产品名称: TNFSF10 polyclonal antibody
英文名称: TNFSF10 polyclonal antibody
产品编号: PAB24882
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TNFSF10.
- Immunogen:
- A synthetic peptide corresponding to TNFSF10.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 30
- Reactivity:
- Human
- Specificity:
- TNFSF10 polyclonal antibody detects endogenous levels of TNFSF10 protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Purity:
- > 95% by SDS-PAGE
- Storage Buffer:
- In 1x PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunofluorescence
- Entrez GeneID:
- 8743
- Gene Name:
- TNFSF10
- Gene Alias:
- APO2L,Apo-2L,CD253,TL2,TRAIL
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 10
- Omim ID:
- 603598
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq
- Other Designations:
- Apo-2 ligand,TNF-related apoptosis inducing ligand TRAIL,tumor necrosis factor (ligand) family, member 10,tumor necrosis factor apoptosis-inducing ligand splice variant delta
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