PFKP (C-term) Peptide
产品名称： PFKP (C-term) Peptide
英文名称： PFKP (C-term) Peptide
产品编号： P3147
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PFKP.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PFKP.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Trifunctional chemical probes for the consolidated detection and identification of enzyme activities from complex proteomes.
Adam GC, Sorensen EJ, Cravatt BF.Mol Cell Proteomics. 2002 Oct;1(10):828-35.
- 2.
- Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB.Genome Res. 1996 Sep;6(9):791-806.
- 3.
- Regional chromosomal assignment of the human platelet phosphofructokinase gene to 10p15.
Morrison N, Simpson C, Fothergill-Gilmore L, Boyd E, Connor JM.Hum Genet. 1992 Apr;89(1):105-6.
- Applications
- Western Blot (Cell lysate)
- The PFKP polyclonal antibody (Cat # PAB3996) is used in Western blot to detect PFKP in Ramos cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with PFKP polyclonal antibody (Cat # PAB3996) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 5214
- Protein Accession#:
- Q01813
- Gene Name:
- PFKP
- Gene Alias:
- FLJ40226,PFK-C,PFKF
- Gene Description:
- phosphofructokinase, platelet
- Omim ID:
- 171840
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM
- Other Designations:
- OTTHUMP00000018966,Phosphofructokinase, platelet type
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Fructose and mannose metabolism
- Galactose metabolism
- Glycolysis / Gluconeogenesis
- Metabolic pathways
- Pentose phosphate pathway