Anti-MYC Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002749P-50ul	solarbio	50ul	960.00元
K002749P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-MYC Polyclonal Antibody
别名	MRTL;MYCC;bHLHe39;c-Myc
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Human Mouse Rat
蛋白分子量	49kDa
Gene ID	4609
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human MYC
性状	液体
Public Immunogen Range	A synthetic peptide of human MYC
Subcellular Locations	Nucleus nucleolus nucleoplasm
Swiss Prot	P01106
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.