PTPRC monoclonal antibody, clone MEM-28 (Biotin)-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
PTPRC monoclonal antibody, clone MEM-28 (Biotin)

PTPRC monoclonal antibody, clone MEM-28 (Biotin)

商家询价

产品名称： PTPRC monoclonal antibody, clone MEM-28 (Biotin)

英文名称： PTPRC monoclonal antibody, clone MEM-28 (Biotin)

产品编号： MAB4578

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
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  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw
进入展台

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native PTPRC.
  • Immunogen:
  • Native purified PTPRC from human thymocytes and T lymphocytes.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 180-220
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with all alternative forms of human CD45 antigen (Leukocyte Common Antigen), a 180-220 KDa single chain type I transmembrane protein expressed at high level on all cells of hematopoietic origin, except erythrocytes and platelets.
  • Form:
  • Liquid
  • Conjugation:
  • Biotin
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In PBS, pH 7.2 (15 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • Flow Cytometry (1:500)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5788
  • Gene Name:
  • PTPRC
  • Gene Alias:
  • B220,CD45,CD45R,GP180,LCA,LY5,T200
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, C
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
  • Other Designations:
  • CD45 antigen,T200 glycoprotein,T200 leukocyte common antigen,glycoprotein,leukocyte-common antigen,protein tyrosine phosphatase, receptor type, c polypeptide

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